Project Description
Esculetin
Basic information
| Product Name | Esculetin (6,7-Dihydroxycoumarin) |
| CAS Number | 305-01-1 |
| Plant Source | Fraxinus rhynchophylla Hance (Cortex Fraxini), hydrolysis-derived bioactive coumarin source |
| Part Used | Bark, Leaf, Herb Aerial Part |
| Appearance | Off-white to pale yellow crystalline powder |
| Storage | Sealed storage at 2–8°C, protect from light and moisture |
Specifications
| Purity (HPLC) | ≥98% |
| Molecular Formula | C₉H₆O₄ |
| Molecular Weight | 178.14 |
| Test Method | HPLC |
| Solubility | DMSO: Freely soluble; Ethanol: Soluble; Methanol: Soluble |
| Technical Note | Data provided for reference only. Please refer to COA for batch-specific information. |
Raw Material & Quality Control
The raw material of Esculetin is derived from Fraxinus rhynchophylla Hance (Cortex Fraxini), in accordance with the standards specified in the Chinese Pharmacopoeia.
Content assay is performed by HPLC analysis following pharmacopoeial testing methods to ensure accurate purity determination and batch-to-batch consistency.
Quality control is conducted using both in-house analytical testing and third-party laboratory verification to ensure compliance with international safety and quality standards.
All production batches are released only after meeting strict internal specifications and regulatory requirements.
What is Esculetin
Esculetin (6,7-Dihydroxycoumarin) is a naturally occurring coumarin derivative widely distributed in traditional medicinal plants such as Fraxinus rhynchophylla Hance, Artemisia capillaris, and mulberry bark.
It is a bioactive small-molecule compound known for its stable chemical structure and diverse biological activities, making it an important raw material in pharmaceutical research, cosmetic formulations, and functional ingredient development.
Due to its natural origin and multi-functional properties, esculetin is commonly used in antioxidant, anti-inflammatory, and skin-protective applications across various industries.
What are the benefits of Esculetin
Antioxidant Activity
Esculetin helps neutralize reactive oxygen species (ROS), reducing oxidative stress and protecting cells from environmental and metabolic damage.
Anti-inflammatory Mechanism
It modulates inflammatory pathways by inhibiting excessive production of pro-inflammatory mediators, supporting reduction of tissue inflammation and irritation.
Metabolic Regulation Support
Esculetin has been studied for its potential role in regulating glucose and lipid metabolism, contributing to metabolic balance and overall physiological stability.
Skin Protective Function
It helps reduce oxidative-induced skin damage, supports melanin regulation, and contributes to maintaining a more even and healthy skin appearance.
Bioactive Research Potential
As a natural coumarin derivative, esculetin is widely used in pharmacological and biochemical research for studying cellular activity and natural compound mechanisms.
Applications of Esculetin
Esculetin is widely used in pharmaceutical research, cosmetic formulations, nutraceutical products, and functional food development due to its natural bioactivity and coumarin-based structure.
Pharmaceutical Applications
Used as a raw material and intermediate in the development of anti-inflammatory, metabolic regulation, and bioactive compound research formulations.
Cosmetic & Personal Care Formulations
Incorporated into skin care products such as creams, serums, and lotions aimed at improving skin condition and supporting oxidative stress protection.
Functional Food & Nutraceuticals
Applied in dietary supplements and functional food products focused on antioxidant support and metabolic balance.
Food Antioxidant Applications
Used as a natural antioxidant ingredient to help improve stability and extend shelf life in certain food formulations.
Scientific Research Use
Widely used in pharmacological and biochemical research as a model compound for studying natural coumarin derivatives.
Solubility Data
| Ethanol (95%) | Soluble |
| Methanol | Soluble |
| DMSO | Freely soluble |
| Water | Slightly soluble |
| Hot Water | Partially soluble under heating |
Solubility data is provided for reference only. Actual formulation performance may vary depending on system conditions.
Product Datasheets
| Certificate of Analysis (COA) |
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Packing&Storage
- 1-5kg with double plastic container inside/aluminum foil bag outside. 10kg with double plastic container inside/carton outside. 25kg with double plastic container inside/fiber drum outside or it is at your option.
- Stored in a cool & dry well-closed container, keep away from moisture and strong light/heat.
- Shelf Life: Two years under well storage situation.
Transport&Payment
- Small package sent by EMS, UPS, FedEx, DHL, etc.
- Payment available for Western Union, T/T, Paypal, etc.
- Cargo sent by Air or By Sea is all available.
By Express By Air By Sea Suitable for under 50kg Suitable for more than 50kg Suitable for more than 500kg Delivery time: 4-5days Delivery time: 5-7days Delivery time: 15-30days Door to door service Airport to Airport Port to Port Easy to pick up the goods Professional broker needed Professional broker needed
Certifications
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