Project Description
Fraxetin (CAS:574-84-5)
Basic information
| Product Name | Fraxetin | Other name | Fraxetol |
|---|---|---|---|
| Plant sources | Fraxinus Chinensis / Cortex Fraxini (Ash Bark) | Brand name | ANIHERB |
| Part Used | Bark | Specification | 98% |
| Molecular Formula | C₁₀H₈O₅ | Active Ingredient | Fraxetin |
| Appearance | Off-White to Light Yellow Crystalline Powder | Grade | Cosmetic, Food & Pharmaceutical Grade |
| Test Method | HPLC | Place of Origin | Shaanxi, China (Mainland) |
Specifications
| Fraxetin | Test Method | Appearance |
|---|---|---|
| 98% | HPLC | Off-White to Light Yellow Crystalline Powder |
What is Fraxetin
Fraxetin (also known as Fraxetol) is a natural phenolic coumarin compound extracted from the bark of Fraxinus species (Cortex Fraxini). It serves as a core bioactive ingredient widely applied in the cosmetics, health supplement and pharmaceutical industries.
Possessing potent anti-inflammatory, antioxidant and photoprotective properties, Fraxetin has gained long-term recognition in skincare and functional formula development. Featuring outstanding skin soothing, antioxidant repairing and light-stabilizing effects, it has become a high-value botanical ingredient for anti-aging, brightening and sensitive skincare products across global markets.
What are Main Components of Fraxetin
Fraxetin is a high-purity single-component coumarin derivative with stable chemical properties and definite functional mechanisms, and its core constituent characteristics are as follows:
Fraxetin (Fraxetol): The exclusive and primary active constituent of Cortex Fraxini purification. It dominates core biological functions, including anti-inflammation, free radical scavenging, ultraviolet resistance and skin brightening, acting as the core quality marker for finished products.
Aesculetin: A homologous natural coumarin compound coexisting with Fraxetin in ash bark. It synergizes with Fraxetin to strengthen antioxidant and anti-inflammatory efficacy and assist in enhancing the overall skin-care and pharmacological activities.
What are the benefits of Fraxetin
Fraxetin is a versatile natural active ingredient with remarkable cosmetic effects and physiological regulatory functions, covering skincare, health care and pharmaceutical applications:
Core Cosmetic & Skin Care Benefits
Anti-Inflammatory & Soothing
Fraxetin effectively inhibits the release of inflammatory mediators, relieves skin redness, external irritation and allergic sensitivity, and calms reactive skin conditions, making it an ideal mild active ingredient for sensitive skin care formulations.
Antioxidation & Anti-Aging
It efficiently scavenges excess free radicals in the skin, alleviates oxidative stress and environmental damage caused by pollution and radiation, improves dull complexion and fine lines, and effectively delays premature skin aging.
Photoprotection & UV Defense
Fraxetin features excellent UV absorption capacity against UVA and UVB radiation, stabilizes light-sensitive ingredients in formulas, and significantly reduces skin photodamage and photoaging induced by long-term sun exposure.
Skin Brightening & Even Tone
It regulates abnormal melanin synthesis and deposition, fades superficial dark spots and sallow skin tone, evens uneven skin texture, and improves overall skin translucency and luminosity.
Antibacterial & Sebum-Regulating
With mild and safe broad-spectrum antibacterial activity, Fraxetin inhibits the proliferation of common skin pathogenic bacteria, regulates facial and scalp sebum secretion, improves oily skin and acne-prone problems, and maintains skin microecological balance.
Health Food & Pharmaceutical Functions
Anti-Inflammatory Support
Fraxetin modulates systemic inflammatory responses, relieves chronic inflammatory discomfort in the body, and provides effective support for joint and physical health maintenance.
Antioxidant Protection
It neutralizes endogenous harmful free radicals, enhances cellular antioxidant defense capacity, and reduces oxidative damage to human tissues and organs.
Vascular Health Support
Modern pharmacological studies verify that Fraxetin protects vascular endothelial activity, improves human microcirculation, and assists in maintaining vascular health.
Traditional Herbal Support
As a key functional component of traditional Cortex Fraxini, Fraxetin inherits the traditional herbal effects of heat-clearing, detoxifying and anti-inflammation, and is widely used in modern refined herbal formulations.
1. Strict Raw Material Selection
We select high-quality natural Fraxinus Chinensis bark from standardized planting bases as raw materials, strictly screening maturity, cleanliness and impurity content to ensure stable and high-quality raw material sources for Fraxetin extraction.
2. Full-process Production Supervision
The whole process of crushing, extraction, purification and refining of Fraxetin adopts standardized SOP management. Real-time process monitoring and batch sampling detection are implemented to guarantee stable intermediate quality and consistent finished product efficacy.
3. Dual Standard Finished Product Testing
We conduct in-house HPLC precision testing to ensure 98% high purity of Fraxetin. Meanwhile, third-party authoritative institutions carry out heavy metal residue, microbial limit and safety toxicology tests to meet global cosmetic, food and pharmaceutical grade standards.
4. Reliable Delivery Standards
All batches of Fraxetin products pass full-item quality inspection before delivery, with stable batch difference and reliable quality, supporting long-term stable bulk supply and customized order services.
Applications of Fraxetin
1. Applications of Fraxetin
Benefiting from its high safety, mild properties and multi-dimensional bioactivities, Fraxetin is widely used in multiple high-end industrial fields.
2. Cosmetics & Personal Care
It is extensively applied in sensitive skin soothing products, anti-redness repair products, anti-aging essences, brightening skincare series, sunscreen products and after-sun repair formulations.
3. Health Food & Dietary Supplements
Used in functional dietary supplements for systemic antioxidant defense, chronic inflammation regulation and daily body health conditioning.
4. Pharmaceutical Industry
Suitable for the development of topical anti-inflammatory and repairing preparations, oral herbal health formulations, and serving as standard reference substances for pharmaceutical quality detection.
5. Laboratory & Research
Widely used as standard reference materials and experimental samples in botanical pharmacology, analytical chemistry and new drug development research.
Solubility Characteristics
| Solvent | Solubility Performance |
|---|---|
| DMSO | Freely soluble |
| Ethanol (95%) | Soluble |
| Hot Water | Soluble |
| Cold Water | Slightly soluble |
Product Datasheets
Packing&Storage
- 1-5kg with double plastic container inside/aluminum foil bag outside. 10kg with double plastic container inside/carton outside. 25kg with double plastic container inside/fiber drum outside or it is at your option.
- Stored in a cool & dry well-closed container, keep away from moisture and strong light/heat.
- Shelf Life: Two years under well storage situation.

Transport&Payment
- Small package sent by EMS, UPS, FedEx, DHL, etc.

- Payment available for Western Union, T/T, Paypal, etc.
- Cargo sent by Air or By Sea is all available.
By Express By Air By Sea Suitable for under 50kg Suitable for more than 50kg Suitable for more than 500kg Delivery time: 4-5days Delivery time: 5-7days Delivery time: 15-30days Door to door service Airport to Airport Port to Port Easy to pick up the goods Professional broker needed Professional broker needed
Certifications

