Project Description

Fraxin 

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Basic information

Product Name Fraxin
CAS Number 524-30-1
Plant Source Fraxinus rhynchophylla Hance (Cortex Fraxini), standardized according to Chinese Pharmacopoeia monograph
Part Used Bark
Specification 98%
Appearance Off-white to light yellow crystalline powder
Grade Cosmetic, Food & Pharmaceutical Grade
Test Method HPLC
Brand ANIHERB
Place of Origin Shaanxi, China (Mainland)

Specifications

Purity (HPLC) ≥98%
Molecular Formula C₁₆H₁₈O₁₀
Molecular Weight 386.31
Test Method HPLC
Storage Condition Sealed storage at 2–8°C, protected from light and moisture
Technical Note Data provided for reference only. Please refer to Certificate of Analysis (COA) for batch-specific results.

Raw Material & Quality Control

The raw material of Fraxin is derived from Cortex Fraxini (Fraxinus rhynchophylla Hance), in accordance with the standards of the Chinese Pharmacopoeia.

The identification and assay of Fraxin are performed using HPLC analysis to ensure accurate quantification and consistent purity across production batches.

Quality control is conducted under strict in-house SOPs, covering raw material selection, in-process monitoring, and final product testing.

Each batch is additionally verified through third-party laboratory testing to ensure compliance with heavy metal, microbial, and safety standards before release.

What is Fraxin

Fraxin is a naturally occurring coumarin glycoside primarily found in the bark of Fraxinus species (Cortex Fraxini). It is structurally related to other plant-derived glycosides such as esculin, but exhibits distinct physicochemical and biological properties.

As a bioactive plant metabolite, Fraxin is widely studied for its role in natural defense mechanisms in plants and is used as a functional ingredient in cosmetic, pharmaceutical, and nutraceutical formulations.

Compared with its aglycone derivatives, Fraxin maintains higher water solubility and stability, making it suitable for formulation systems requiring balanced solubility and mild biological activity.

What are Main Components of Fraxin

Fraxin is a single glycosidic coumarin compound derived from Cortex Fraxini, with a well-defined molecular structure and high chemical purity when standardized through HPLC analysis.

Fraxin (Primary Active Compound)

The main bioactive constituent responsible for its core chemical identity and functional properties. It is a coumarin glycoside structure combining a coumarin nucleus with sugar moieties, contributing to its solubility and stability.

Hydrolysis-Related Derivative (Esculetin)

Under specific conditions, Fraxin may undergo partial hydrolysis to form esculetin, a structurally related aglycone compound with enhanced lipophilicity and distinct biological activity.

What are the Benefits of Fraxin

Skin Soothing Support

Fraxin helps support skin comfort by modulating irritation responses, making it suitable for sensitive and reactive skin formulations.

Formulation Stability Advantage

Due to its glycosidic structure, Fraxin provides improved water compatibility and stability in cosmetic and aqueous formulation systems.

Mild Antioxidant Protection

It contributes to the reduction of oxidative stress in topical systems, helping maintain product and skin condition stability.

Photoprotection Support

Fraxin has been studied for its role in supporting skin defense against environmental stressors, including UV-induced oxidative damage.

Synergistic Cosmetic Performance

It works well in combination with other plant-derived actives, enhancing overall formulation performance in skincare products.

Strict Raw Material Selection

We source high-quality botanical raw materials from controlled origins, ensuring consistency and traceability from the very first step of production.

Full-Process Manufacturing Control

All production stages including extraction, purification, and refinement are managed under standardized SOPs with continuous in-process quality monitoring.

Multi-Level Quality Testing System

Each batch undergoes in-house HPLC testing for purity and specification control, combined with third-party laboratory verification for heavy metals, microbial limits, and safety compliance.

Regulated Release Standards

Products are released only after passing all internal and external quality inspection requirements, ensuring stable and reliable product quality for global clients.

Technical & Regulatory Support

We provide COA, MSDS, and technical documentation to support formulation development, regulatory registration, and international market compliance.

Applications of Fraxin

Fraxin is widely used in cosmetic formulations, pharmaceutical research, and functional ingredient development due to its mild bioactivity and excellent formulation compatibility.

Cosmetics & Personal Care Formulations

Suitable for skin care products such as creams, lotions, serums, and essences, especially for sensitive skin, soothing, and skin-conditioning applications.

After-Sun & Protective Skincare Products

Commonly used in after-sun care and protective skincare formulations to support skin comfort and help reduce environmental stress effects.

Functional Skincare Ingredient Systems

Used as a supporting ingredient in multi-active cosmetic systems to enhance formulation stability and overall product performance.

Pharmaceutical & Research Applications

Applied in pharmaceutical research and natural compound studies as a reference material for coumarin glycoside-related investigations.

Nutraceutical & Functional Development

Explored in functional health product development due to its plant-derived origin and mild bioactive profile.

Solubility Characteristics

DMSO Freely soluble
Ethanol (95%) Soluble
Methanol Soluble
Water Slightly soluble
Hot Water Partially soluble under heating

Solubility data is provided for formulation reference only. Actual performance may vary depending on system composition and processing conditions.

Product Datasheets

Certificate of Analysis (COA)

COA

Download COA

Packing&Storage

  1. 1-5kg with double plastic container inside/aluminum foil bag outside. 10kg with double plastic container inside/carton outside. 25kg with double plastic container inside/fiber drum outside or it is at your option.
  2. Stored in a cool & dry well-closed container, keep away from moisture and strong light/heat.
  3. Shelf Life: Two years under well storage situation.

plant extract package

Transport&Payment

  1. Small package sent by EMS, UPS, FedEx, DHL, etc.
  2. Payment available for Western Union, T/T, Paypal, etc.
  3. Cargo sent by Air or By Sea is all available.
    By Express By Air By Sea
    Suitable for under 50kg Suitable for more than 50kg Suitable for more than 500kg
    Delivery time: 4-5days Delivery time: 5-7days Delivery time: 15-30days
    Door to door service Airport to Airport Port to Port
    Easy to pick up the goods Professional broker needed Professional broker needed

     

Certifications