Project Description

Esculin

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Basic information

Product Name Esculin Other Name Aesculin, Esculoside
Plant Source Fraxinus rhynchophylla Hance (Cortex Fraxini), Chinese Pharmacopoeia standard source Part Used Bark
Specification 98% Test Method HPLC
Appearance Off-white to light yellow crystalline powder Grade Cosmetic, Food & Pharmaceutical Grade
Molecular Formula C15H16O9 Place of Origin Shaanxi, China (Mainland)

Specifications

Esculin Test Method Appearance
98% HPLC Off-White to Light Yellow Crystalline Powder

Raw Material & Quality Control

Raw material of Esculin is derived from the dried bark of Fraxinus rhynchophylla Hance, as specified in the Chinese Pharmacopoeia.

Content assay is performed using HPLC analysis in accordance with Chinese Pharmacopoeia standards to ensure accurate quantification and consistency.

The product is standardized using Esculin reference substance issued by the National Institutes for Food and Drug Control (NIFDC), ensuring compliance with official pharmacopeia requirements.

What is Esculin

Esculin (also known as aesculin) is a natural coumarin glycoside compound extracted from the bark of Fraxinus rhynchophylla.

It is a bioactive plant-derived ingredient widely used in cosmetic, pharmaceutical, and nutraceutical formulations due to its antioxidant, anti-inflammatory, and photoprotective properties.

Esculin is commonly applied in skincare formulations targeting skin soothing, brightening, and protection against environmental stress.

What are Main Components of Esculin

Esculin is a naturally occurring coumarin glycoside and is considered a single purified bioactive compound rather than a multi-component extract.

Esculin (Aesculin)

The main active form responsible for its antioxidant, anti-inflammatory, and photoprotective biological activities.

Aesculetin (Related Metabolite)

Aesculetin is the hydrolyzed aglycone form of esculin, which shares similar antioxidant and anti-inflammatory properties.

What are the benefits of Esculin

Anti-inflammatory Mechanism

Esculin helps modulate inflammatory mediators, reducing oxidative stress and supporting skin barrier stability.

Antioxidant Protection

It scavenges free radicals and helps protect skin cells from environmental and UV-induced oxidative damage.

Photoprotective Activity

Esculin absorbs UV-related stress and helps reduce photoaging effects caused by long-term sun exposure.

Skin Brightening Support

It helps regulate melanin activity and supports improvement of uneven skin tone and dull complexion.

Formulation Stability Advantage

Esculin exhibits good compatibility in cosmetic formulations and can enhance stability in sensitive skincare systems.

Aniherb Product Advantage

1. Strict Raw Material Traceability

We source high-quality Fraxinus bark from controlled regions with full traceability from raw material collection to final extraction, ensuring consistent starting quality.

2. Standardized Production System

All manufacturing processes are conducted under strict SOPs, including extraction, purification, and refining, ensuring stable product quality and batch-to-batch consistency.

3. Dual Quality Control System

We implement in-house HPLC testing combined with third-party laboratory verification to ensure purity, safety, and compliance with international standards.

4. Global Supply Capability

With stable production capacity and a mature supply chain, we ensure reliable delivery for global cosmetic, pharmaceutical, and nutraceutical customers.

Applications of Esculin

Esculin is widely used in cosmetic, pharmaceutical, and research applications due to its anti-inflammatory, antioxidant, and photoprotective properties.

Cosmetics & Personal Care

Used in anti-redness, brightening, anti-aging, and sensitive skin formulations such as creams, serums, lotions, and after-sun products.

Sun Care & Skin Protection Products

Applied in sunscreen and after-sun formulations to help reduce UV-induced oxidative damage and photoaging effects.

Pharmaceutical Applications

Used in topical anti-inflammatory preparations and herbal formulations targeting skin irritation and microcirculation support.

Functional Skincare Formulations

Incorporated into advanced skincare systems designed for skin barrier protection, tone improvement, and oxidative stress reduction.

Laboratory & Research Use

Used as a reference compound in pharmacological and cosmetic ingredient research studies.

Solubility Characteristics

Solvent Solubility
DMSO Freely soluble
Ethanol (95%) Soluble
Water Soluble
Cold Water Slightly soluble

Product Datasheets

Certificate of Analysis (COA)
 

COA PDF

Download COA

Packing&Storage

  1. 1-5kg with double plastic container inside/aluminum foil bag outside. 10kg with double plastic container inside/carton outside. 25kg with double plastic container inside/fiber drum outside or it is at your option.
  2. Stored in a cool & dry well-closed container, keep away from moisture and strong light/heat.
  3. Shelf Life: Two years under well storage situation.

plant extract package

Transport&Payment

  1. Small package sent by EMS, UPS, FedEx, DHL, etc.
  2. Payment available for Western Union, T/T, Paypal, etc.
  3. Cargo sent by Air or By Sea is all available.
    By Express By Air By Sea
    Suitable for under 50kg Suitable for more than 50kg Suitable for more than 500kg
    Delivery time: 4-5days Delivery time: 5-7days Delivery time: 15-30days
    Door to door service Airport to Airport Port to Port
    Easy to pick up the goods Professional broker needed Professional broker needed

     

Certifications